Wednesday, 30 October 2013

N-carboxy-glycin n-benzyl ester USES and production methods


Purpose: 1 N - carboxy - glycin N - benzyl ester used in peptide synthesis, used for amino acid monomer. 2 organic intermediates. 3 as a peptide reagents. 4 and biochemical studies
Production methods: under the cooling, formic acid benzyl ester chloride and sodium hydroxide solution of drop added to the mixture of glycine and sodium hydroxide solution, while stirring. Reaction, let stand for the reservoir. Water cooling after acidification were extracted with ethyl ether to Congo red acid, filter the precipitation, water washing, drying, product benzyl oxygen carbonyl glycine. Yield of 86-91%.

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From:Biochemical Reagent

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