Terpeptin A is a novel peptide recently isolated from Aspergillus terreus, which inhibits the cell cycle at G2/M phase. Molecular weight: 497.3128. Terpeptin A and B, two new members of the indolic enamides, were identified from a strain of Aspergillus sp.
Terpeptin, a novel peptide having cell cycle inhibitory activity, was isolated from the cultured broth of Aspergillus terreus 95F -1 and its structure was elucidated by spectral analyses. Terpeptin inhibited the cell cycle progression of mouse tsFT210 cells in the G2/M phase with a minimum inhibitory concentration of 62.5, it is a new spiroketal, named aspergiketal (1) was isolated from the culture broth of Aspergillus terreus, an endophytic fungus in the stems of the plant Opuntia.
Molecular formulae: C28H40N4O4, Cytotoxic Constituents of Aspergillus terreus from the Rhizosphere of Opuntia versicolor of the Sonoran Desert Cytotoxic Constituents of Aspergillus terreus from the Rhizosphere of Opuntia versicolor of the Sonoran Desert.
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