Sunday, 29 December 2013

Information about CAN ELISA Kit



Calcineurin (CAN) is a protein phosphatase also known as protein phosphatase 3, and calcium-dependent serine-threonine phosphatase. It activates the T cells of the immune system and can be blocked by drugs. Calcineurin activates nuclear factor of activated T cell, cytoplasmic (NFATc), a transcription factor, by dephosphorylating it. The activated NFATc is then translocated into the nucleus, where it upregulates the expression of interleukin 2 (IL-2), which, in turn, stimulates the growth and differentiation of T cell response. Calcineurin is the target of a class of drugs called calcineurin inhibitors, which includes cyclosporine, pimecrolimus and tacrolimus.
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From:Elisa assay kits

Friday, 27 December 2013

What is COMP ELISA Kit?



Cartilage oligomeric matrix protein(COMP)is a protein that in humans is encoded by the COMP gene.
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein.It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfide bonds. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudoachondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).


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Thursday, 26 December 2013

A brief introduction Cholesteryl oleate (Cholesterol oleate)



AS no. : 303-43-5
English name: Cholesteryl oleate
English synonyms: cholestreyloleate; Oleoylcholesterol; CHOLESTEROL OLEATE; CHOLESTERYL OLEATE; Cholesteroyl - oleate; Cholestereyl oleate; CHOLESTERYL OLEATE by 97%; CHOLESTERYL OLEATE (RG); Cholesteryl oleate, 99 + %; CHOLESTERYL OCTADECENOATE
Chinese name: cholesterol oleic acid ester
English synonyms: LCD CO. Oleic acid cholesterol ester; Oleic acid cholesterol ester; Cholesterol oleate; Oleic acid cholesterol ester; Cholesteryl oleic acid ester; Cholesteric alkenyl oleic acid ester; Cholesterol oleic acid ester, 97%; Cholesterol oleate, LCD CO. Cholesteryl oleic acid ester/cholesterol oleic acid ester
CBNumber: CB2274304
Molecular formula: C45H78O2
Molecular weight: 651.1
MOL File: 43-303-5. MOL
Oleic acid cholesterol ester chemical properties
Melting point: 44-47 ° C (lit.)
The refractive index: - 20 ° C = 2, THF)
Flash: > 230 ° F
Storage conditions: - 20 ° C

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Tuesday, 24 December 2013

Information about CK-MB ELISA Kit


In the advance of a analytic allegory involving 204 alongside absolute creatine kinase (CK), creatine kinase-MB isoenzyme (CK-MB), and cardiac troponin I (cTnI) measurements, 12 patients were articular in whom cTnI was animated while absolute CK was normal, as able-bodied as 2 patients in whom CK-MB was animated while cTnI was normal. CK-MB about basis was animated in 6 of the twelve cTnI-positive patients with accustomed absolute CK; alone 2 of these patients had a acquittal analysis of astute myocardial infarction (AMI). All of the 12 patients in this accumulation had medical altitude that are associated with greater accident for astute cardiac events. Both patients with accustomed cTnI but animated absolute CK and CK-MB basis had abiding renal insufficiency; one of these patients had a absolute accent analysis and a analysis of AMI. The added cTnI-negative accommodating died 2 canicule afterwards admission, and dissection appear affirmation of ischemic changes, but not astute infarction. Significant differences were credible amid acceptable CK-MB after-effects and cTnI measurements. Using absolute CK acclivity as a prerequisite for consecutive CK-MB altitude may absolute the analytic acuteness of this agitator brand for audition subacute ischemic accident to the myocardium. Animated absolute CK and CK-MB isoenzyme after agnate elevations in cTnI, on the added hand, may reflect changes in agitator abolishment kinetics due to renal failure, or cross-reactivity of the cTnI appraisal with non-cardiac antigens.

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Thursday, 19 December 2013

Oxymetazoline Hcl's use manual



Drug instructions: per milliliter hydrochloride eye drops containing 250 mu g hydroxyl methyl thiazole moiety, 14 mg polyethylene alcohol (liquid membrane elements), 40 mu g benzene alkyl ammonium chloride and in accordance with the acid disodium, polyvinylpyrrolidone, sodium acetate, sodium chloride and water. Eye drops: 0.025% x 5 mL.
Functional indications: Oxymetazoline Hcl is a kind of thiazole moiety derivative, is a contraction of vascular function is proposed to the sympathetic nervous drugs, its purpose is to direct stimulation of alpha 1 - receptor on vascular smooth muscle (postsynaptic receptor), which has curative effect effect quickly and relatively permanent, and the characteristics of the low bounce sexual orientation. Used to alleviate the eye symptoms of allergic conjunctivitis, non infectious conjunctivitis and lifted by allergy, dry eye, swimming, smoke, contact lenses, fatigue caused by factors such as bloodshot eyes.
Usage and dosage: 1 to 2 drops/times, once every eight hours.
Note: cannot mydriatic patients (such as primary closed-angle glaucoma and severe patients with narrow Angle) and disabled patients allergic to the drug ingredients. Uncontrolled hypertension, arrhythmia, diabetes, hyperthyroidism patients and are systemic application of monoamine oxidase inhibitors with caution.

Tuesday, 17 December 2013

The purpose of Viaminate


Viaminate for vitamin A acid derivatives and structured approximate total trans vitamin A acid, mechanism of action and 13 - vitamin A acid and aromatic vitamin A acid is similar, but the side effects is lighter all trans vitamin A acid. Oral with adjustment and control of epithelial cell differentiation and growth, inhibition of diversification, reduce sebum secretion, inhibit cutin cell keratin process formation, abnormal keratinization returned to normal, restrain the growth of the acne propionic acid bacteria, and can regulate immune and anti-inflammatory effects. Treatment of acne, the Angle of abnormal sex skin disease, ichthyosis, psoriasis (psoriasis), lichen class skin, mucous membrane disease, connective tissue disease also have certain curative effect, etc. This product is A vitamin A acid derivatives and structured approximate total trans vitamin A acid, mechanism of action and 13 - vitamin A acid and aromatic vitamin A acid
A similar, but side effects is lighter all trans vitamin A acid. Oral with adjustment and control of epithelial cell differentiation and growth, inhibition of diversification, reduce sebum secretion, inhibit cutin cell keratin process formation, abnormal keratinization returned to normal, restrain the growth of the acne propionic acid bacteria, and can regulate immune and anti-inflammatory effects.

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Friday, 13 December 2013

What is dronedarone?



Dronedarone is a biologic by Sanofi-Aventis, mainly for the adumbration of cardiac arrhythmias. It was accustomed by the FDA on July 2, 2009. It was recommended as an another to amiodarone for the assay of atrial fibrillation and atrial agitate in humans whose hearts accept either alternate to accustomed accent or who abide biologic assay or electric shock assay i.e. absolute accepted cardioversion ( DCCV ) to advance accustomed rhythm. However, the FDA did not accept dronedarone for abbreviation deaths.A balloon of the biologic in affection abortion was chock-full as an acting assay showed a accessible access in affection abortion deaths, in patients with abstinent to astringent CHF.
In adjustment for dronedarone to be FDA accustomed the architect had to add a Black box warning, advertence that Multaq is contraindicated in patients with NYHA Class IV affection failure, or NYHA Class II–III affection abortion with a contempo decompensation acute analysis or barometer to a specialized affection abortion clinic." The FDA alerted healthcare professionals to attenuate cases of astringent alarmist accident associated with the use of dronedarone.


Thursday, 12 December 2013

Prazosin hydrochloride has any adverse reaction?



Most Prazosin hydrochloride can cause syncope caused by orthostatic hypotension occurred occasionally in the ventricular rate for ~ / point usually after the first dose ~ minutes or with other antihypertensive agents share there was a low sodium diet and share of beta blockers if change the first dose to patients more easily happen. Mg bedtime taking can prevent or mitigate the adverse reactions; The day before to this drug is to stop using diuretic "phenomenon for the first time" the effect can also be reduced if there are self-limited in most cases won't happen again
. Dizziness and drowsiness may occur after the medication for the first time after the first medication or add quantity on the first day should avoid driving and dangerous job dizzy can occur in position by lying to stand up slowly to avoid and dizzy in drinking prolonged standing movement or the weather is hot also can appear so in these cases should be careful with prazosin hydrochloride tablets
Adverse reaction of the rate of % of vertigo (. %), headache (. %) sleepiness (. %) mental difference (. %) palpitations (. %), nausea (. %) more adverse reactions can occur at the beginning of the drug tolerance;
Other adverse reaction rates for % ~ % the following vomiting diarrhea constipation edema orthostatic hypotension dizziness with syncope depression excitable itchy rash to urinate blurred vision sclera congestion blocked nose nose bleeding
Adverse reactions have abdominal pain of abdominal discomfort of lower incidence % of abnormal liver function pancreatitis tachycardia paresthesia illusion hair flat lichen incontinence impotence penis priapism other occasional adverse reactions tinnitus fever sweating arthritis and antinuclear antibody positive.

Monday, 9 December 2013

What is the purpose of the ciprofloxacin



Ciprofloxacin for synthesis of the second generation of quinolone antibacterial drugs, with broad-spectrum antibacterial activity, bactericidal effect is good, for almost all bacteria antimicrobial activity of norfloxacin and in accordance with the strong effect of 2 ~ 4 times, for e. coli, pseudomonas aeruginosa, h. influenzae, neisseria gonorrhoeae, legionella bacteria, staphylococcus aureus, streptococcus has antibacterial effect.
Ciprofloxacin clinical USES the norfloxacin is wide, in addition to the urinary tract infection, intestinal infection, and gonorrhea thereof, can be used to treat the flu bacilli, escherichia coli, klebsiella pneumoniae, singular proteus, the common proteus, providence, bacteria, Morgan coli, pseudomonas aeruginosa, sewer enterobacter, Frau cedrat coli, staphylococcus aureus (including methicillin-resistant strains) of bone and joint infection, skin soft tissue infection and pneumonia, sepsis, etc. The goods of oral preparations of indications with norfloxacin; Intravenous drug delivery can be used in the treatment of infection of the heavier, such as enterobacteriaceae bacterial sepsis, pulmonary infection, abdominal cavity, biliary infection, etc.


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From:Natural herbal extracts

Friday, 6 December 2013

L - Leucine profile




Leucine is one of 20 kinds of basic amino acids, it and isoleucine are isomers. On the nutrition, leucine is human body essential amino acids.
Leucine is most commonly occurs in the protein, amino acids and period for infants and children develop normally and adults are both important nitrogen balance within the body. Presumably, leucine may be in the balance of protein in the biochemical and decomposition method to maintain the muscles of accounts for an important role.
Are a major source of food for leucine are: whole grain, milk, dairy products, eggs, pork, beef, chicken, beans, leafy vegetables.
Preparation: the manufacture of amino acid hydrolyzed protein from 1820 began. 1908 Ikeda found that sodium glutamate is Japanese flavour enhancer, started the history of the industrial production of amino acid. Glutamic acid with microbial fermentation production of Japan started in 1957, since then opened a new chapter of the history of the microbial fermentation method producing amino acids. Around 60 s of the 20th century, about a L leucine biosynthesis and metabolic regulation mechanism have been elucidated. This for the L leucine directional breeding microorganism fermentation production and enzymatic production L leucine provides a theoretical basis.
L a leucine main production methods of extraction, chemical synthesis method, enzyme catalysis, microorganism fermentation, etc.


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From:polypeptides

Tuesday, 3 December 2013

The summary of Donefezil





Donepezil, marketed beneath the barter name Aricept by its developer Eisai and accomplice Pfizer, and aswell marketed beneath the cast name DONEP by Alkem Pentacare, is a centrally acting capricious acetylcholinesterase inhibitor.Its capital ameliorative use is in the booze analysis of Alzheimer's disease.Common ancillary furnishings cover gastrointestinal upset. It has an articulate bioavailability of 100% and calmly crosses the blood–brain barrier. Because it has a biological half-life of about 70 hours, it can be taken already a day.
Currently, no absolute affidavit shows the use of donepezil or added agnate agents alters the advance or progression of Alzheimer's ache (AD). However, 6 to 12-month controlled studies accept apparent bashful allowances in acknowledgment and/or behavior.Pilot studies accept appear donepezil analysis may potentially accept furnishings on markers of ache progression, such as hippocampal volume. Therefore, abounding neurologists, psychiatrists, and primary-care physicians use donepezil in patients with Alzheimer's disease. In 2005, the UK National Institute for Clinical Excellence (NICE) withdrew its advocacy for use of the biologic for mild-to-moderate AD, on the base of no cogent advance in anatomic outcome, superior of life, or behavioral symptoms. However, NICE revised its guidelines to advance donepezil be acclimated in moderate-stage patients for whom the affirmation is strongest.


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From:Natural herbal extracts

Thursday, 21 November 2013

Diazepam can cure various diseases





Diazepam, aboriginal marketed as Valium /ˈvæliəm/ by Hoffmann-La Roche, is a benzodiazepine drug.
It is frequently acclimated to amusement anxiety, agitation attacks, insomnia, seizures (including cachet epilepticus), beef spasms (such as in tetanus cases), active legs syndrome, booze withdrawal, benzodiazepine withdrawal, analgesic abandonment affection and Ménière's disease. It may aswell be acclimated afore assertive medical procedures (such as endoscopies) to abate astriction and anxiety, and in some surgical procedures to abet amnesia.
It possesses anxiolytic, anticonvulsant, hypnotic, sedative, ashen beef relaxant, and amnestic properties. The pharmacological activity of diazepam enhances the aftereffect of the neurotransmitter GABA by bounden to the benzodiazepine website on the GABAA receptor (via the basic chlorine atom) arch to axial afraid arrangement depression.


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From:Natural herbal extracts

Wednesday, 20 November 2013

The purpose of Hafnium Carbide is introduced




Purpose: Hafnium Carbide is very suitable for rocket nozzle, for re-entry space rocket nose cone parts. Used in ceramic industry, etc. Of nature: nature: 12.7 g/cm3 density, melting point 3890 ℃, the highest melting point in a single compound is known. Volume resistivity Ω 1.95 x 10-4 cm (2900 ℃), thermal expansion coefficient of 6.73 x 10-6 / ℃. Usually use hafnium (HfO2) and carbon composite powder in the inert or reducing atmosphere, reaction temperature 1900 ~ 2300 ℃ can hafnium carbide with many compounds (such as ZrC, TaC) form a solid solution. High melting point and high elasticity, good electric conductivity, small thermal expansion and good impact resistance.

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From:pharmaceutical chemicals

Sunday, 17 November 2013

Information about Anti-Collagen I(Anti--Collagen Type I)





Collagen is the capital structural protein of the assorted affiliation tissues in animals. (The name collagen comes from the Greek kolla acceptation cement and suffix -gen cogent producing.) As the capital basic of affiliation tissue, it is the a lot of abounding protein in mammals, authoritative up from 25% to 35% of the whole-body protein content. Collagen, in the anatomy of continued fibrils, is mostly begin in coarse tissues such as tendons, ligaments and skin, and is aswell abounding in corneas, cartilage, bones, claret vessels, the gut, and intervertebral discs. The fibroblast is the a lot of accepted corpuscle which creates collagen.
In beef tissue, it serves as a above basic of the endomysium. Collagen constitutes one to two percent of beef tissue, and accounts for 6% of the weight of strong, tendinous muscles. Gelatin, which is acclimated in aliment and industry, is collagen that has been irreversibly hydrolyzed.


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From:Elisa test kits

Thursday, 7 November 2013

The basic information of the 9,9-Dioctyl-2,7-dibromofluorene





CAS Number: 198964-46-4
English name: 9,9-Dioctyl-2 ,7-dibromofluorene
English Synonyms: 9,9-Dioctyl-2 ,7-dibroMoflurene; 9,9-Dioctyl-2 ,7-dibromofluorene; 9,9-Dioctyl-2 ,7-diformylfluorne; 9,9-DioCLyl-2 ,7-DibroMofluorene ; 9,9-DIOCTYL-2 ,7-DIFORMYLFLUORENE; 2,7-DibroMo-9 ,9-dioctyl fluorine; 2,7-Dibromo-9 ,9-di-n-octylfluorene; 9 9-DIOCTYL-2 7 - DIBROMOFLUORENE 96; 9H-Fluorene, 2,7-dibroMo-9 ,9-dioctyl-; 9H-Fluorene, 2,7-dibroMo-9 ,9-dioctyl-2,7-DibroMo-9 ,9-bis (n-octyl) fluorene
Chinese name: 9,9 - dioctyl -2,7 - two dibromofluorene
Chinese Synonyms: 9,9 - two octyl-2 ,7 - dibromofluorene; 9,9 - dioctyl -2,7 - two bromo; 2,7 - dibromo -9,9 - di-n-octyl fluorene; 9,9 - dioctyl -2,7 - two dibromofluorene; 9,9 - two octyl-2 ,7 - dibromo fluorene; 2,7 - dibromo -9,9 - dioctyl -9H-fluorene; 2,7 - dibromo-9 ,9 - dioctylfluorene 9,9 - dioctyl-2 ,7 - dibromo fluorene
CBNumber: CB9504859
Formula: C29H40Br2
Molecular Weight: 548.44
MOL File: 198964-46-4.mol
9,9 - dioctyl -2,7 - two dibromofluorene chemical properties
Melting Point: 59-63 ° C (lit.)


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From:chemical materials

Tuesday, 5 November 2013

The magic of Dianabol





Methandrostenolone(Dianabol) reacts acerb with the androgen receptor but still exerts its furnishings through the androgen receptor in vivo. These cover affecting increases in protein synthesis, glycogenolysis, and beef backbone over a abbreviate amplitude of time. In top doses (50 mg ), ancillary furnishings such as gynecomastia, top claret pressure, abscess and macho arrangement alopecia may activate to occur. The biologic causes astringent masculinising furnishings in women even at low doses. In addition, it is metabolized into methylestradiol by aromatase. This agency that after the administering of aromatase inhibitors such as anastrozole or aminoglutethimide, estrogenic furnishings will arise over time in men. Many users will action the estrogenic ancillary furnishings with Arimidex, Nolvadex or Clomid. In addition, as with added 17α-alkylated steroids, the use of methandrostenolone over continued periods of time can aftereffect in alarmist accident after adapted care.
The 17α-methylation of the steroid does acquiesce it to canyon through the alarmist with alone a baby allocation of it torn down (hence causing the above accident to the liver) acceptance it to be able if taken orally. It aswell has the aftereffect of abbreviating the steroid's affection for sex hormone bounden globulin, a protein that de-activates steroid molecules and prevents them from added reactions with the body. As a result, methandrostenolone is decidedly added alive than an agnate abundance of testosterone, consistent in accelerated advance of beef tissue. However, the accessory acclivity in estrogen levels - a aftereffect of the aromatization of methandrostenolone - after-effects in cogent baptize retention. This gives the actualization of bad assets in accumulation and strength, which prove to be acting already the steroid is discontinued and baptize weight drops. Because of this, it is generally acclimated by bodybuilders alone at the alpha of a "steroid cycle", to facilitate accelerated backbone increases and the actualization of abundant size, while compounds such as advance hormone or nandrolone with continued acting esters physique up in the physique to an apparent bulk able of acknowledging anabolic action on their own.


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From:Natural herbal extracts

Sunday, 3 November 2013

The purpose of the silver powder




Paint with aluminum powder (also called silver powder) is scaly particles, it is for this scaly particles state, aluminium powder with metallic and shielding function. Metal aluminium industrial production has a long time ago, in the early production mode is pounding method and pounded the aluminium scraps on impact machine of the slots, pestles under mechanical drive continuous play the slots of aluminum, is malleable aluminum under the impact of gradually into thin slices and crushing, screening after aluminum became very little tiny, as a product meets the requirements of aluminum powder. Dao method production efficiency is low, the quality of the product is not easy to master, and dust during production, very easy to fire and explosion. In 1894, German Hamtag with ball mill production of aluminum powder, put the ball in the ball mill, aluminum scrap and lubricant, make use of the flying ball break after becoming flaky aluminum powder of aluminum, in ball mill and pipe filled with inert gases, this method is still in use, called "dry process production. In 1910, the United States, J.H all invented to join oil solvent instead of inert gas inside the ball mill, the production of aluminum powder and solvent composite slurry, paste aluminium powder pigment. This method is simple in equipment, process safety, product very convenient, quickly adapted for use by countries around the world. Most modern aluminium powder pigment is using this method, this method is also called the "wet".

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From:Metallic powders

Friday, 1 November 2013

Zinc introduction




Zinc, in business aswell spelter, is a brownish actinic element; it has the attribute Zn and diminutive amount 30. It is the aboriginal aspect of accumulation 12 of the alternate table. Zinc is, in some respects, chemically agnate to magnesium, because its ion is of agnate admeasurement and its alone accepted blaze accompaniment is +2. Zinc is the 24th a lot of abounding aspect in the Earth's band and has 5 abiding isotopes. The a lot of accepted zinc ore is sphalerite (zinc blende), a zinc sulfide mineral. The better mineable amounts are begin in Australia, Asia, and the United States. Zinc assembly includes barm abutment of the ore, roasting, and final abstraction application electricity (electrowinning).
Brass, which is an admixture of chestnut and zinc, has been acclimated aback at atomic the 10th aeon BC. Zinc metal was not produced in ample calibration until the 12th aeon in India, while the metal was alien to Europe until the end of the 16th century. The mines of Rajasthan accept accustomed audible affirmation of zinc assembly traveling aback to 6th Aeon BC.To date the oldest affirmation of authentic zinc comes from Zawar, Rajasthan as aboriginal as 9th aeon AD, if distilation action was active to accomplish authentic zinc.Alchemists austere zinc in air to anatomy what they alleged "philosopher's wool" or "white snow."


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From:metal material

Wednesday, 30 October 2013

N-carboxy-glycin n-benzyl ester USES and production methods


Purpose: 1 N - carboxy - glycin N - benzyl ester used in peptide synthesis, used for amino acid monomer. 2 organic intermediates. 3 as a peptide reagents. 4 and biochemical studies
Production methods: under the cooling, formic acid benzyl ester chloride and sodium hydroxide solution of drop added to the mixture of glycine and sodium hydroxide solution, while stirring. Reaction, let stand for the reservoir. Water cooling after acidification were extracted with ethyl ether to Congo red acid, filter the precipitation, water washing, drying, product benzyl oxygen carbonyl glycine. Yield of 86-91%.

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From:Biochemical Reagent

Mandelic Acid profile



Mandelic Acid to white slice rhombic crystal, dew with light discoloration decomposition. Soluble in ether and isopropyl alcohol, soluble in water and ethanol. Mandelic acid is one of the hydrolysis product of amygdalin, earliest and by j. w. Walker and v. k. Krieble in 1909 made by amygdalin was hydrolyzed by dilute hydrochloric acid. Mandelic acid and its derivatives in the body are epinephrine and norepinephrine sheets amine oxidase and catecholamine metabolites - O - methyl transferase. Mandelic acid molecules have a chiral carbon atoms, hence the (R) and type (S) of the two enantiomers. (R) - type gradually racemization in the 160 ° C. Isomers with cresol acid (2 - hydroxy - 3 - methyl benzoic acid) and 2 - methoxy benzoic acid.

Friday, 25 October 2013

Information about Ureaplasma urealyticum genotyped detection kit (PCR-reverse some hybrid method)




Original body includes six species of urea, urea solution urea original body (Ureaplasma urealyticum) have close relationship with human urinary tract infection. Urea solution urea also called soluble m. urealyticum in the original body, can use their urea enzyme, after the decomposition of urea to provide energy metabolism. On the classification of genus mycoplasma urea original body genera. Urea solution urea original body is one of the human urinary tract common parasitic bacteria, in certain circumstances can cause disease. In engraftment of human body can have the second rise, namely the childbirth by the maternal birth canal neonatal infection, after rapidly reduced; Starting from the sex life and gradually increase. In recent years, the urea urea solution is taken seriously increasingly, the original body caused by urinary tract infection is one of the pathogens of urethritis of sex of gonococcus of cause blame. Has been listed as the pathogens of sexually transmitted diseases.

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From:Elisa assay kits

Wednesday, 23 October 2013

P - Chlorophenyl isocyanate should study the synthesis methods of phosgene route

P - Chlorophenyl isocyanate is an important organic synthetic intermediate, it is widely used in chemical, pharmaceutical and other industries. In terms of drug synthesis, the products are mainly used for synthetic drugs fall blood sugar. Currently, P - Chlorophenyl isocyanate synthesis method is given priority to with phosgene and react to chloroaniline, the method of preparation of P - Chlorophenyl isocyanate yield is high, but as a result of phosgene as highly toxic gas, large damage to the environment, and the measurement and operation is not very convenient, so it is necessary to explore the synthesis methods of phosgene route. 

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From:Chemistry chemicals materials

The basic information of the 2,3-Dichlorothiophene



English synonyms: 2, 3 - dichloro thiophene. 2, 3 - dichloro thiophene, 97%
English name: 2, 3 - Dichlorothiophene
English synonyms: 2, 3 - DICHLOROTHIOPHENE; 2, 3 - Dchlorothiophene; 2, 3 - DICHLOROPYRIDINE; Thiophene, 2, 3 - dichloro -
CAS no. : 17249-79-5
Molecular formula: C4H2Cl2S
Molecular weight: 153.03
EINECS no. :
Related categories: Thiophens; Thiophene. Halogenated Heterocycles; Heterocyclic Building Blocks. Thiophenes. ThiophenesBuilding Blocks; thiophene
Mol files: 17249-79-5. Mol


Monday, 21 October 2013

Lymecycline some effect





Lymecycline is a tetracycline broad-spectrum antibacterial marketed by the biologic aggregation Galderma. It is about 5,000 times added acrid than tetracycline abject and is different amidst tetracyclines in that it is captivated by an alive carriage activity beyond the abdominal wall, authoritative use of the aforementioned fast and able apparatus by which carbohydrates are absorbed.
The greater assimilation of lymecycline allows for lower dosages to be used; the accepted dosage of 408 mg is agnate to 300 mg tetracycline abject and, in its action, to 500 mg tetracycline hydrochloride. Lymecycline, clashing tetracycline hydrochloride, is acrid at all physiological pH values.


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From:Natural herbal extracts

Friday, 18 October 2013

Hydroxylethyl methylimidazolium saccharinate related matters





Packaging and storage and transportation
Packing: double bag, outer composite paper bag, inner polyethylene film bag.
Storage: hydroxylethyl methylimidazolium saccharinate stored in indoor and ventilated dry place, pay attention to moistureproof. Rain in the process of transportation, prevent bask in.
Safety matters
1. The product there is the danger of dust explosion, when a large number of processing or bulk processing need to be careful to avoid the dust deposition and suspended in the air, can't close to the heat, Mars, flame and electrostatic.
Methyl cellulose powder and into 2. Avoid contact with eyes, should be worn when operating the filter mask and safety goggles.
3. The product is very slippery when wet, and methyl cellulose powder should be clear in time, and disposal of the skid.


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From:Catalyst chemistry

Tuesday, 15 October 2013

Losartan D4 medical applications





Cozaar (Losartan D4) first listed in 1994 , is now in 93 countries have been approved for use for the treatment of hypertension . Hyzaar including the United States have been in 74 countries have been approved for use .
Merck currently apply in some countries outside the United States Cozaar treatment of heart failure indications. And have been registered in 12 countries for the treatment of those who are no longer suitable for the application of angiotensin -converting enzyme inhibitor (ACEI) therapy.
Cozaar and Hyzaar are AIIA class of drugs most prescribed drugs in the world, sales of anti-hypertensive drugs qualifying third . Since the advent of the drug , there have been more than 10 million patients who have taken Cozaar and Hyzaar . As these drugs Cozaar most widely studied drugs , there are more than 4,000 scientific papers published . Cozaar and Hyzaar are developed by Merck .
In order to assess the therapeutic effect of Cozaar , especially in improving hypertension, heart failure and recent heart attack survival rates , reduce morbidity , it has already launched a series of large-scale endpoint studies, including LIFE ( Cozaar treatment of hypertension survival Study ) and OPTIMAAL ( Cozaar after myocardial infarction study ) .
For Cozaar Kidney Protection Study (RENAAL) has published the annual meeting of American Society of Hypertension . This new landmark study achieved its primary goal , the first time demonstrated Cozaar for hypertension associated with type 2 diabetic nephropathy patients with renal protection . Cozaar group in patients with end-stage renal disease risk reduction of 28 %, usually these patients require dialysis and kidney transplant to maintain life .
Advances in clinical medicine
Calcium channel blockers and losartan in patients with hypertension can reduce the risk of gout (BMJ. 2012 Jan 12; 344: d8190. Doi: 10.1136/bmj.d8190.)
Topic : Different types of antihypertensive drugs on the incidence of gout : a population-based case-control study (Antihypertensive drugs and risk of incident gout among patients with hypertension: population based case-control study.)
Objective: This study was designed to study the application of antihypertensive drugs in patients with hypertension and the risk of gout independent association between .
Design: nested case- control study .
Setting : UK General Practice Research Database Health 2000-2007 .
Study subjects: 24,768 cases aged 20-79 years adult patients with gout , 50,000 cases of the control group were randomly paired samples .
Key indicators: antihypertensive drugs associated with the application of the relative risk of gout onset .
Results: The age, gender, body mass index , medical status, alcohol and drugs and related complications after adjustment for patients with hypertension (N = 29138) antihypertensive drug-related causes gout multivariate relative risks were: calcium channel antagonists 0.87 ( 95% confidence interval 0.82 to 0.93 ) , losartan 0.81 ( 0.70 to 0.94 ) , diuretics 2.36 (2.21至2.52), β receptor antagonists 1.48 ( 1.40 to 1.57 ) , angiotensin-converting inhibitors 1.24 ( 1.17 to 1.32 ) , non- angiotensin Ⅱ receptor antagonist losartan 1.29 ( 1.16 to 1.43 ) . Non-hypertensive patients studied yielded similar results. Hypertensive patients with calcium channel antagonists length of time multivariate relative risks were: <1 year 1.02,1-1.9 years 0.88, ≥ 2 years was 0.75 , while losartan were 0.98,0.87 and 0.71 (P for trend <0.05 ) .
CONCLUSIONS: Consistent with decreased uric acid , calcium channel antagonists and losartan in patients with hypertension can reduce the risk of gout . In contrast , diuretics , β receptor antagonists, angiotensin converting enzyme inhibitors and non- losartan angiotensin Ⅱ receptor antagonist associated with increased risk of gout .


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From:Natural herbal extracts

Monday, 14 October 2013

DARPP-32 (Phospho-Thr34) Polyclonal Antibody related presentations




Cancer is a disease, abnormal proliferation and differentiation, but also diseases abnormal apoptosis. The process of gastric lesions, reduced apoptosis, proliferation increases may be related to cell regulation disorders. Survivin is an inhibitor of apoptosis protein, in the developing embryos and human malignancies, expressed in transformed cell lines, and in the terminal differentiation and maturation of tissue hardly expressed. Survivin expression in tumors with poor prognosis, tumor progression, relapse, drug treatment was well tolerated and patients shortened survival. So the location and function of survivin in the conduct of research that can guide clinical diagnosis and treatment is to provide a theoretical basis. Survivin may be through inhibition of caspase activity play its anti-apoptotic function. Found that protein phosphorylation pathways involved in the regulation of cell death, affected subcellular localization, cell protection and cell cycle progression. Survivin mainly in the G2 / M phase expressed in vivo during mitosis, the cell cycle-dependent kinase complex (P34cdc2-cyclinB1) so that the first 34 survivin protein threonine (Thr34) phosphorylation. Phosphorylation of survivin with microtubule polymerization or mitotic spindle, inhibit caspase9 activity. Survivin variants (Thr34-Ala, 34 threonine replaced by alanine) although capable of binding to the mitotic apparatus, but the loss of phosphorylation sites, survivin-caspase9 complexes during mitosis device lost contact occurs caspase9 dependent apoptosis. Phosphorylation defective survivin mutant (Thr34-Ala) expression of the body can cause human melanoma cell line apoptosis, and may increase the sensitivity to chemotherapeutic drugs. Therefore, the first survivin peptide chain 34 is the impact of survivin threonine functional areas. The present study aimed phosphorylated survivinThr34 in gastric carcinoma and distribution, in order to facilitate the diagnosis and treatment of gastric provide a new target. Materials and methods 1. Second Affiliated Hospital of China Medical University Collection 2001-2003 resected gastric lesions and endoscopic biopsy tissue sections 108 cases. 2. Immunohistochemistry Reagents later, polyclonal goat anti-human antibody survivinThr34 phosphorylated. 3.Adopt counted under a microscope for positive semi-quantitative analysis. 4. Statistically using xZ test to determine statistically significant differences between samples. Results 1. Immunohistochemical detection of phosphorylated sUrVivinTllr34 protein mainly distributed in the cytoplasm of gastric adenocarcinoma, in adjacent neighboring tissue can also be seen phosphorylated sulvMn Thl.34 protein expression, but a small number. Phosphorylated stirvivinTh has 4 protein expression and gastric adenocarcinoma patients' gender, age, histological grade, pathological staging. 2 dysplasia, gastric benign lesions expression rates were 33.3% and 35.3%, by statistical analysis of phosphorylated s ~ ivihThi have 4 in the above two kinds of pathological conditions expressed positive rate difference. 3 phosphorylated s ~ ivinT Bu r34 proteins in gastric adenocarcinoma, the positive expression rate was 76.79%, with atypical hyperplasia, benign gastric lesions group, by x, analysis P0.01, was statistically significant . Discussion 1. The experimental results show that the phosphorylation of proteins in gastric adenocarcinoma sulvivinThr34 highly expressed in atypical hyperplasia, benign gastric lesions low expression in adjacent tissue section adjacent expression. It is felt that there is phosphorylated survivinThr34 proliferation and differentiation of tissues were expressed. High expression in gastric cancer cells, expression of the strong, may be associated with cell proliferation, differentiation exuberant about. 2 adjacent neighboring cells in the cuvette phosphorylated 4 survivin expression, although these cells did not change shape in the light microscope, but have changed at the molecular level, they will eventually develop into cancer cells or normal cells carrying self-repair, pending further study. 3 phosphorylated survivinTh has 4 protein expression in benign gastric lesions may be related to the repair of damaged gland cells to maintain normal cell function. Conclusions phosphorylated survivin bamboo ir34 distributed only in the cytoplasm. . Phosphorylation of survivin in gastric adenocarcinoma dish code 4 expression was significantly increased, although it is not specific markers of gastric adenocarcinoma, but can be used as reference for the diagnosis of gastric adenocarcinoma, gastric cancer cells as a facilitator intervention sites. 3.Thi has four functional areas as survivin, phosphorylated survivinTI] 134 expression may be associated with cell proliferation, involved in cell differentiation, and is glandular cell damage repair factor, maintaining the integrity and regulating gastric mucosal cell renewal .

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From:Raw pharmaceutical materials

Friday, 11 October 2013

Bifidobacterium Bifidum related information





Bifidobacterium number distribution in the gastrointestinal phase of growth and decreased with age , the distribution is the most nutritious children breast milk . It has been found , Bifidobacterium 32 subtypes , Bifidobacterium biologics containing up to 70 . Intestinal bacteria Bifidobacterium infantis sixty percent of the total , over 60 years old accounted for only 7.9 percent of bifidobacteria .

Response to oxygen
The sensitivity of members of the genus Bifidobacterium to O2 generally limits probiotic activity to anaerobic habitats. Recent research has reported that some Bifidobacterium strains exhibit various types of oxic growth. Low concentrations of O2 and CO2 can have a stimulatory effect on the growth of these Bifidobacterium strains. Based on the growth profiles under different O2 concentrations, the Bifidobacterium species were classified into four classes: O2-hypersensitive, O2-sensitive, O2-tolerant, and microaerophilic. The primary factor responsible for aerobic growth inhibition is proposed to be the production of hydrogen peroxide (H2O2) in the growth medium. A H2O2-forming NADH oxidase was purified from O2-sensitive Bifidobacterium bifidum and was identified as a b-type dihydroorotate dehydrogenase. The kinetic parameters suggested that the enzyme could be involved in H2O2 production in highly aerated environments


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From:Lactic acid bacteria

Wednesday, 9 October 2013

Probiotic classification




Probiotics (Probiotics, Probiotic) is a class of beneficial microorganisms to the host, is planted in the human intestinal tract, reproductive system, which can produce the exact health benefits to improve the host micro-ecological balance, play a useful role in the activity of beneficial microorganisms in general. The human body, animals, beneficial bacteria or fungi are: Clostridium, Lactobacillus, Bifidobacterium, Lactobacillus acidophilus, actinomycetes, yeasts and so on. Research on the world's most powerful types of products are mainly above composite active probiotic microorganisms, which are widely used in biological engineering, industry, agriculture, food safety, and life and health fields.
Category:
(1) Lactobacillus
(Such as Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus Jane's Raman Lactobacillus, etc.)
(2) Class Bifidobacterium
(Such as Bifidobacterium longum, Bifidobacterium breve, Bifidobacterium oval thermophilus Bifidobacterium)
(3) Gram-positive cocci
(Such as Streptococcus faecalis, Lactococcus, Streptococcus and other intermediaries).
Precautions probiotic products and purchase
Yogurt, but with probiotics is limited, and many people do not fit to take.
Probiotic solid drink. Dietary supplements on the market under the cartridge powdered probiotic solid beverage, and its advantages are easy to carry, convenient to eat. It can be eaten directly, or adding reconstituted juice and milk consumption, more and more work and traveling families of all ages. And its strains can vary according to the characteristics of populations and physiological adjustments, bacteria content is relatively high, usually to 30 billion.
Probiotics such as infant formula is one important component
Probiotic strains survive environmental requirements for the production and packaging process has very high standards, domestic technology has not yet reached to provide for the effective probiotic strains kept alive packaging environments.
Need to recognize the time of purchase on the packaging clearly identify strains, such as: cheese Lactobacillus Zhang, Bifidobacterium BB-12, Lactobacillus rhamnosus LGG, Lactobacillus acidophilus NCFM, Lactobacillus plantarum P-8, Bifidobacterium V9 , Bifidobacterium lactis HN019.
Fungi
Some yeasts also classified as probiotics category....



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From:Food bacteria

Tuesday, 8 October 2013

Vitamin K-related information




Vitamin K is a group of naphthoquinone derivatives 2 - menadione, is a human vitamins, with a hydrophobic. It is a special post-translational protein necessary, particularly in the blood coagulation protein necessary. Vitamin K2 (menaquinone (Menaquinone) and four Menatetrenone (Menatetrenone)) is usually manufactured by bacteria in the intestines of animals, so vitamin K deficiency is extremely rare unless there is severe intestinal damage. In addition to natural vitamin K1, K2, there are also synthetic vitamin K3, K4.
Vitamin K is a family of compounds of similar structure, their common methylated naphthoquinone ring, but at position 3 of the hydrocarbon side chain is different. Phylloquinone (Phylloquinone. Also known as vitamin K1) with the side chain of four isoprene (isoprenoid) residues, one of which is unsaturated known. Menadione (Menaquinone, vitamin K2) an unsaturated side chain known unequal number of isoprene chains, commonly referred to as MK-n, n represents the number of isoprene chains. MK-4, 5,7 equal activity with vitamin K1. MK-1 only 1% of the activity of vitamin K1, MK-10 is only 30 to 49% of the active. Menadione (Menadione, vitamin K3) is a synthetic product, but with toxicity.


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From:Herbal extract

Thursday, 29 August 2013

Sodium Sulphide Solid role




Sodium Sulphide Solid, inorganic compounds, also known as stink alkali, soda smelly, yellow alkali, sodium sulfide. Pure sodium sulfide is a colorless crystalline powder. Strong moisture absorption, soluble in water. Solution is strongly alkaline reaction. Contact with skin and hair will cause burns. Therefore, commonly known as sodium sulfide sulfide. Aqueous sodium sulfide in the air will slowly oxidize thiosulfate, sodium sulfite, sodium sulfate and sodium polysulfide. As faster generation of sodium thiosulfate, the main product of oxidation is sodium thiosulfate. Sodium sulfide in the air deliquescence, and carbonated and deterioration, constantly release hydrogen sulfide gas. Industrial sodium sulfide containing impurities its color was pink, brown, khaki. Weight, melting point, boiling point, but also due to impurities varies.
Role purpose:
1 dye industry for the production of sulfur, hydrogen sulfide and sulfide blue material;
2 dissolved sulfur dyeing industry as a co-agent;
3 tanning industry for the hydrolysis of rawhide hair removal, but also for the preparation of polysulfide to accelerate the soaking of dry skin soft. Paper and paper industry as a cooking agent;
4 rayon denitration for the textile industry and the reduction of nitro compounds, as well as cotton fabric dyeing mordant;
5 pharmaceutical industry for the production of phenacetin and other antipyretic drugs. In addition, for the system sodium thiosulfate, sodium hydrosulfide, sodium sulfide and more.


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From:Metal materials

Wednesday, 28 August 2013

Sodium Tripolyphosphate (Food Gra) the nature and indications




Properties: Sodium Tripolyphosphate (Food Gra), also known as trisodium phosphate. Significant twelve hydrate and anhydrate. Anhydrous as white crystals. Density 2.536g/cm3. Melting point 1340 ℃. Twelve monohydrate is a colorless cubic crystal or white powder. Density 1.62g/cm3. Melting point 73.3 ℃. 76.7 ℃ decomposition. Heated to 100 ℃ 12 crystal water loss from anhydrous. In dry air easily weathered. Are soluble in water, solubility in 20 °-120g / L; 30 degrees-163g / L. Its solution is strongly alkaline. Not soluble in carbon disulfide and ethanol. Of phosphoric acid with sodium carbonate and the reaction solution, control the pH value of 8 to 8.4, after the filtered cake residue, the filtrate was concentrated, so that the liquid caustic soda Na / P ratio of 3.24 to 3.26, and then by cooling and crystallization, solid separated, dried and prepared. Anhydrous sodium phosphate dodecahydrate based crystals were dissolved in the heated to 85 ~ 90 ℃ of water (10% to 15%), after dehydration in the system. Can be used as soft water and detergents, boiler scale inhibitor, the fixing toner printing, silk fabric enhancer, metal corrosion inhibitor and metal rust inhibitors, enamel flux and the production of bleaching agents, the system the rawhide leather degreasing agent and degumming agents. Food grade phosphate dodecahydrate emulsifiers used in food processing, quality improver, nutritional supplements, and food with a bottle (tank) of the detergent.
Indications: polycythemia vera, essential thrombocythemia, chronic myelogenous leukemia, chronic lymphocytic leukemia, as well as to identify the nature of superficial tumors, but also for neurodermatitis, chronic eczema, capillary tumors, keloids, winging pterygium, corneal neovascularization, plasma cell tumors of the applicator treatment.


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From:Metal materials

Tuesday, 27 August 2013

A brief history of the discovery of Sulphur




Sulfur (Sulphur) is a non-metallic element, chemical symbol is S, atomic number is 16. Sulfur Sulphur is a very common nonmetallic tasteless, pure sulfur is yellow crystals, also known as sulfur. In nature it is often in the form of sulfide or sulfate, pure sulfur in volcanic areas are also appearing in nature. It is an integral part of many amino acids. Mainly used in fertilizers, gunpowder, lubricants, pesticides and the production of anti-fungal agents. Generating combustion of sulfur dioxide in the air with oxygen and water to form sulfuric acid, causing acid rain.
Around 4,000 years ago, the Egyptians would have been formed by the combustion of sulfur dioxide to bleach cloth, the ancient Greeks and Romans also be proficient in the use of sulfur dioxide fumigation and bleaching. The ninth century BC, the Roman poet Homer in his writings about the sulfur burning when disinfecting and bleaching effect.
In ancient China, the first pharmaceutical monograph "Shen Nong's Herbal Classic" [1], contained in the animals, plants and minerals up to 365 kinds of medicines, contained 46 kinds of minerals in drugs, there are stone sulfur (ie sulfur). In this book there is also pointed out: "Stone sulfur can turn Yellow Gold iron, strange things." This shows that the sulfur was already known to work with copper, iron and other metals to form metal sulfides directly. World's oldest extant writings alchemy - Wei Boyang of the "Kinship" [2], but also chronicles the sulfur and volatile mercury can be less volatile mercury sulfide synthesis. Chinese study for gunpowder, probably began in the seventh century AD. Then black gunpowder gunpowder, which is composed of potassium nitrate, sulfur and charcoal composed of three. Sulfur is an important component of black powder was.
With the 1746 British J.Roebuck lead chamber method invented in 1777 manufacture of sulfuric acid and sulfur by the French ALLavoisier recognized as an element, the sulfur will enter the gates of modern chemistry. After this time, the sulfur is fast becoming the modern chemical industry and the modern chemical industry is closely related to one of the most important elements. Latin name Surphur estimates of sulfur from India Sanskrit Sulvere, the original meaning is bright yellow.


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From:Metal materials

Sunday, 25 August 2013

Zinc Oxide 99.7% of the usage history


Zinc oxide (ZnO), commonly known as zinc white, a zinc oxide. Insoluble in water, soluble in acid and alkali. Zinc oxide is a commonly used chemical additives, is widely used in plastics, silicate products, synthetic rubber, lubricants, paints, ointments, adhesives, food, batteries, flame retardants and other products production. Zinc oxide bandgap and a large exciton binding energy, high transparency, excellent performance often Wen Faguang in the semiconductor field of liquid crystal display, thin film transistors, light emitting diodes and other products are applied. Furthermore, zinc oxide fine particles as a nano-material in the relevant fields have begun to play a role.
Using History
Early humans learned to use it as a paint or zinc oxide topical medicine, but the history of mankind discovered zinc oxide has been difficult to trace.
In ancient Indian medicine book "Chakra The collection" describes a zinc oxide after being identified as a drug, used to treat eye diseases and injuries. 1st century AD Greek physician Dioscorides Clerides also mentioned to do with zinc oxide ointment. Avicenna completed in 1025, "Hui prescription" will be described as zinc oxide to treat various skin disorders, including skin cancer drug of choice. Nowadays, people are no longer using zinc oxide cure skin cancer, it is still widely used to treat other common skin disorders.
Romans as early as 200 BC, they learn how to use copper and zinc ore containing zinc oxide reaction produced brass. Zinc oxide zinc in the shaft furnace turned into steam, rolled into the flue react. Dioscorides Clerides also been introduced to this.
12th century onwards, the Indians know the zinc and zinc, and began using zinc smelting original way. Zinc smelting technology was introduced to China in the 17th century. 1743, Bristol, England, established the first European zinc smelting factory.
Another major use of zinc oxide is used as a coating, known as zinc white. In 1834, zinc white first became watercolor paints, but zinc white insoluble oil. But soon the problem of zinc oxide produced by the new process solutions. In 1845, in Paris, Leclerc began mass production of zinc white oil paint, to 1850, zinc white became popular throughout Europe. High purity zinc white, so that in the 19th century, some artists in painting painted zinc white as a background, however, after a hundred years later, these paintings are showing cracks.
In the latter half of the 20th century, zinc oxide is used in the rubber industry. In the 1970s, the second largest use of zinc oxide is copy paper additives, but in the 21st century, zinc oxide additive approach for copy paper has been eliminated.

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From:Metal materials

Thursday, 22 August 2013

Shipbuilding Plate Background and uses





Shipbuilding Plate refers to special structural steel shipbuilding production for the manufacture of the ocean, coastal and inland navigation ship hull structure steel sheets and thick steel plate.

Background:
Since 2011, the international shipping market downturn, shipbuilding overcapacity, resulting in the shipbuilding industry has entered a "winter period."
Experts pointed out that the international financial crisis, the impact of lag, shipbuilding real crisis has only just arrived, the current new orders declined significantly impact the next three years will be gradually upgraded. Authoritative data show that the first three quarters of last year, about 30% of the national shipyard did not receive new orders and new ship prices than last year before the financial crisis Heavy 30% -40%. Let shrinking shipbuilding shipbuilding plate market also suffered a weakness.

Purpose:
Shipbuilding plate is mainly used for domestic shipbuilding industry. Shipbuilding plate by different rolling equipment production, China's shipbuilding plate production with the development of shipbuilding industry composition is also changing, due to the different properties of the products rolling equipment there is a difference, shipbuilding plate prices are not the same, and in a certain market supply and demand environment more clearly reflected.


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From:Metal materials

Tuesday, 20 August 2013

Tool Steel (51-100) in a carbon tool steel




Tool Steel (Tool Steel (51-100)), is used to manufacture cutting tools, measuring tools, dies and wear-resistant tool steel. Tool steel with high hardness and high temperature can maintain high hardness and red hardness, and high wear resistance and appropriate toughness. Tool steel is generally divided into carbon tool steel, alloy tool steel and high speed tool steel.
Carbon tool steel carbon mass fraction is higher, at 0.65-1.35%, and their organizations are hypoeutectoid, or eutectoid eutectoid steel. Carbon tool steel heat treated to receive a higher surface hardness and wear resistance, the center has good toughness; annealed low hardness (less than HB207), good processing properties. But its red hardness difference, when the working temperature up to 250 ℃, the hardness and wear resistance of a sharp decline, down to HRC60 hardness below the hardenability of these steels is low. Larger tools can not hardenability (water quenching diameter of 15mm), water quenched when the center of the surface hardened layer with hardness vary greatly. Makes the tool easy to produce deformation during quenching. Or the formation of cracks addition, the quenching temperature range is narrow, the quenching temperature should be strictly controlled. Prevent overheating, decarburization and deformation.



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From:Metal materials

Tuesday, 13 August 2013

What is Flourspar Powder?



Flourspar Powder halide minerals. The main components of calcium fluoride of the formula CaF2. In the ultraviolet ray irradiation or a cathode, blue green fluorescence. Sometimes yttrium and cerium rare earth elements. Equiaxed crystal, crystal often cube, octahedron, rhombic dodecahedron and so on. Collection of dense granular or lumpy. Often has green, blue or purple, or colorless and transparent. Vitreous luster, Mohs hardness 4, a completely octahedral cleavage. Specific gravity 3.18. Mainly in hydrothermal veins. Often associated with sphalerite, galena symbiosis. Colorless fluorite in granitic pegmatite veins or fluorite crystal cave. Preparation of hydrofluoric acid is the main raw material, also used as enamel, glass, cement manufacturing ingredients and metallurgical industry flux, and as a rocket fuel catalyst. Colorless, transparent optical lens can be made by. China is the largest country in the world fluorspar production, the main origin of Zhejiang, Hunan and Fujian. The world's major origin of South Africa, Mongolia, the United States, Russia, Thailand and Spain.

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From:Metal materials

Monday, 12 August 2013

What is Fluorspar Lumps?




Fluorite is the industry's main source of fluorine, which is widely used in aerospace, refrigeration, pharmaceuticals, corrosion, fire, electrical, mechanical, and nuclear and other fields. Fluorite resource-rich country, many deposits, reserves, production and export volume ranking first in the world.
Fluorite, also known as fluorspar(Fluorspar Lumps), is the industry's main source of fluorine, the world's 20 several important non-metallic mineral raw materials. Pure colorless fluorite can be used as an optical material, beautiful color fluorite gem stone and also as arts and crafts carving raw materials. Fluorite is fluorine chemical industry's basic raw materials, its products are widely used in aerospace, aviation, refrigeration, pharmaceuticals, pesticides, anti-corrosion, fire, electronics, electrical, mechanical and nuclear and other fields. With the continuous development of technology and the economy, fluorite has become an important modern industrial mineral raw materials, many developed countries regard it as an important strategic material for reserves. Chinese fluorite resource-rich, widely distributed, many deposit types, resources, reserves, production and export volume ranking first in the world. Ancient Indians found that there is a small hill on the Cobra particularly large, they are always wandering around in a big rock. One of the natural phenomena cause people to explore the mysteries of interest. Originally, when night fell, where the big stone slightly blue light flashes, and many insects have phototaxis stone would have come to light over the flying frog jumped out to competing predator insects, hiding not far from the Cobra have also come predation frog. Thus, the people of this stone is called "Snake Eyes Stone." Later learned that Snake Eyes is fluorite stone.
The ingredient is calcium fluoride fluorite, also known as fluorspar, Fei stone, because it contains a variety of rare elements and often has purple, green, light blue, colorless and transparent fluorite rare and precious. There are crystal cube, octahedron or rhombic dodecahedron. If put into the ultraviolet fluorescent fluorite according to a photo, it will issue a beautiful fluorescence.
The use of fluorite and its processed products have been involved in more than 30 industrial sectors. Fluorite added steel refining, can improve the melt fluidity of sulfur and phosphorus to remove harmful impurities.
Half of the world for the manufacture of fluorite production of hydrofluoric acid, the development of manufacturing Cryolite for aluminum smelting industry. The fridge coolant (Freon) to use fluorite; 1986, China's first generation of artificial blood should be used fluorite. Scientists are developing fluoride glass optical fiber communication may produce a new material that can pass through 20,000 kilometers wide in the Pacific instead of being re-issued station.
Production throughout the world. Fluorite Fluorite, also known as fluorspar, chemical composition of CaF2, crystals are equiaxed halide minerals. In the ultraviolet ray irradiation or heating the cathode when the blue or violet fluorescence, and hence the name. Crystal appearing cube, octahedron, or cube interspersed twins, collection of granular or lumpy. Light green, purple or colorless, transparent, sometimes red roses, white streak, vitreous luster, transparent to opaque. Octahedral cleavage completely. Mohs hardness is 4, the proportion of 3.18. Fluorite is mainly produced in hydrothermal veins. Colorless fluorite crystals in granitic pegmatite veins or fluorite crystal cave. World's total reserves of about 1 billion tons of fluorite, China is the world's one of the largest mineral fluorite, and accounted for 35% of world reserves, according to archaeological excavations that, seven thousand years ago, Zhejiang Yuyao Hemudu people, has selected the firefly stone as decorations. Hemudu fluorite mine south indeed exist. Mainly in Zhejiang, Hunan, Fujian and other places. World's other major origin of South Africa, Mexico, Mongolia, Russia, the USA, Thailand, Spain and other places. Fluorite flux used in the metallurgical industry, in the chemical industry raw material for the manufacture of hydrofluoric acid.


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From:Metal materials

Tuesday, 6 August 2013

Lead Ore is an important ore minerals refined lead




Lead Ore is an important ore minerals refined lead, lead is blue-gray metal, the new fracture with brilliant metallic luster. The solid state density is 11.35 g / cm 3, a melting point of 327.4 ℃, boiling point of 1525 ℃, pure lead metal is the most flexible, Mohs hardness of 1.5. Lead has good malleability, ductility but very small, intolerant tension. Very low thermal conductivity of lead, equivalent to 7.5% of silver, conductivity is very poor, and only 7.77% of silver.
Lead with high chemical stability, in dry air at room temperature when no chemical changes. Lead soluble in dilute nitric acid, sulfuric acid at room temperature and hydrochloric acid insoluble lead. Hydrochloric acid and sulfuric acid at room temperature only role and lead surfaces, as PbCl2 and PbS04 generated virtually insoluble, attached to the lead on the surface of the internal metal from corrosion. Lead and alkali, ammonia, chlorine solution and organic acids, esters are not react.
Because lead is acid and alkali corrosive nature, wider use, if we can use him to manufacture various components of chemical equipment, metallurgical plant cell, communication cable sheathing materials, as well as doing batteries, etc.; also be made Babbitt alloy I-lead bearing alloy of lead can absorb radioactive rays, it is used X-ray industrial and nuclear industry, lead compounds used in paints, ceramics, glass, rubber, petroleum refining and other industries can be used for solder, printed alloy.


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From:Metal materials